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Pulmopres 20mg - Cipla Limited - Drug Information

Pulmopres 20mg

Drug brand named Pulmopres 20mg is manufactured by Cipla Limited and mainly contents the generic drug Tadalafil.
Package: 10 x 1

Active Ingredients of Pulmopres 20mg

Tadalafil 20 mg

Can we use Pulmopres 20mg during pregnency

Pregnancy C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and wellcontrolled studies in humans but potential benefits may warrant use of the drug in pregnant women despite potential risks

Can we use Pulmopres 20mg during lactation

Lactation L5 Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience or it is a medication that has a high risk of causing significant damage to an infant The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding The drug is contraindicated in women who are breastfeeding an infant

For what type of diseases Pulmopres 20mg may be prescribed

Erectile dysfunction

What are the known Side Effects of Pulmopres 20mg

Nausea stomach upset skin rash acute toxicity

Precautions before taking Pulmopres 20mg

The breakdown and elimination of tadalafil from the body may be decreased by erythromycin ketoconazole Nizoralitraconazole Sporanox indinavir Crixivan and ritonavir Norvir Therefore these drugs may increase the levels of tadalafil in the blood If these drugs are being used at the same time as tadalafil the dose of tadalafil should be reduced in order to avoid side effects from high levels of tadalafil

Significance of Pulmopres 20mg

Tadalafil is an oral drug that is used for treating impotence the inability to attain or maintain a penile erection andbenign prostatic hyperplasia BPH It is in a class of drugs called phosphodiesterase inhibitors that also includes sildenafil Viagra andvardenafil Levitra Erection of the penis is caused by the filling of the penis with blood Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis and at the same time the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the penis The nitric oxide causes an enzyme guanylate cyclase to produce cyclic guanosine monophosphate cGMP It is cGMP that is primarily responsible for increasing and decreasing the size of blood vessels carrying blood to and from the penis respectively and causing an erection When the cGMP is destroyed by another enzyme phosphodiesterase5 the blood vessels return to their normal size blood leaves the penis and the erection ends Tadalafil prevents phosphodiesterase5 from destroying cGMP so that cGMP stays around longer The persistence of cGMP leads to a more prolonged engorgement of the penis with bloodThe mechanism whereby tadalafil improves the symtoms of BPH is not clear but phosphodiesterase5 also is present in the muscles of the bladder and the prostate and it has been suggested that the relaxation of these muscles may make the passage of urine less difficult for example by reducing the pressure in the muscle surrounding the opening to the urethra that controls the flow of urine from the bladder Tadalafil was approved by the FDA in November 2003

06.03.2013. 02:42