Lumether Forte Tab 6sDrug brand named LUMETHER FORTE TAB 6S is manufactured by THEMIS MEDICARE LIMITED and mainly contents the generic drug Artemether.
Active Ingredients of LUMETHER FORTE TAB 6SArtemether 80mg Lumefantrine 480mg
Can we use LUMETHER FORTE TAB 6S during pregnencyPregnancy D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans but potential benefits may warrant use of the drug in pregnant women despite potential risks
Can we use LUMETHER FORTE TAB 6S during lactationLactation L4 There is positive evidence of risk to a breastfed infant or to breastmilk production but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant eg if the drug is needed in a lifethreatening situation or for a serious disease for which safer drugs cannot be used or are ineffective
For what type of diseases LUMETHER FORTE TAB 6S may be prescribedSevere falciparum malaria cerebral malaria multidrug resistant malaria
What are the known Side Effects of LUMETHER FORTE TAB 6SNausea stomach upset skin rash acute toxicity
Precautions before taking LUMETHER FORTE TAB 6SThis drug should not be used with the following medications because very serious interactions may occur artemetherlumefantrine chloroquine halofantrine ketoconazole quinidine quinine ziprasidoneDo not take halofantrine or ketoconazole for 15 weeks after your last dose of mefloquineTell your doctor of all prescription and nonprescription drugs you may use especially of betablockers eg atenolol propranolol live bacterial vaccines drugs for seizures eg carbamazepine phenytoinvalproic acid drugs affecting liver enzymes that remove mefloquine from your body such as rifamycins including rifabutin and rifampin and azole antifungals including itraconazole and ketoconazole
Significance of LUMETHER FORTE TAB 6SArtemether is a methyl ether derivative of dihydroartemesinin It is similar to artemesinin in mode of action but demonstrates a reduced ability as a hypnozoiticidal compound instead acting more significantly to decrease gametocyte carriage Similar restrictions are in place as with artemesinin to prevent the development of resistance therefore it is only used in combination therapy for severe acute cases of drugresistant P falciparum It should be administered in a 7 day course with 4 mgkg given per day for 3 days followed by 16 mgkg for 3 days Side effects of the drug are few but include potential neurotoxicity developing if high doses are given